Most Asia-Pacific markets were set to open lower on Wednesday, extending a selloff amid an escalating Middle East war.

Follow the latest news after the U.S. and Israel launched a massive attack on Iran that killed Iran's Supreme Leader Ayatollah Ali Khamenei.

China's factory activity faltered in February as manufacturers paused production and cargo shipment to celebrate an extended holiday.

The Dow Industrials ended Tuesday's session down just over 400 points. The 30-stock index curtailed its losses after falling more than 1,200 points at the low.

CNBC's Emma Graham flew home to the UAE on an Emirates flight that turned around just 30 minutes from Dubai because of an Iran missile threat.

Founder and CEO George Kurtz made a compelling argument that we agree with, so why can't the rest of the market get behind him? 

Chinese Premier Li Qiang is set to announce economic targets and policies for the year ahead on Thursday.

In an all-hands meetings with OpenAI employees on Tuesday, CEO Sam Altman said his company doesn't get to choose how the military uses its technology.

Jim Cramer Jim Cramer warns investors not to panic during war-driven market volatility.

Mick Mulvaney also said prediction markets, by offering contracts on events such as wars, could represent a security risk for the U.S.